This textbook provides insights into emerging zoonotic threats from swine, covering the fundamentals of swine biology to the complexities of zoonotic disease transmission. It includes information on both the emergence and impact of swine health on public well-being. Each chapter is supplemented with prevention and control strategies, addressing the impact of swine-borne viruses on human health. A separate chapter addresses the impact of farming practices on public health and the one-health approach, emphasizing the interconnectedness of swine, humans, and the environment. The textbook also discusses surveillance and monitoring techniques for detecting zoonotic diseases in swine populations, highlighting threats posed by pathogens such as Swine influenza, Nipah virus, and Streptococcus suis. Further chapters emphasize emerging viruses, parasitic worms, and bacterial infections. Additionally, it covers the role of vaccination, diagnostic techniques, and biosecurity measures in controlling and mitigating these diseases, while also addressing the importance of risk communication and education in raising awareness. This textbook is relevant for veterinarians, researchers, policymakers, and public health professionals alike, providing insights into the intersection of swine health and public health. It also serves as a resource for professionals seeking to understand and address the challenges of swine zoonoses.