A leading textbook in the internal medicine field for more than 25 years, this publication is based on a continually updated electronic database, where new and updated information is fully integrated monthly, and the entire database published annually in print. Each annual edition contains up to as much as 40% new and updated information, published in 2 volumes with four-color illustrations throughout. The text covers all of internal medicine, plus bio-terrorism and medical emergencies, dermatology, office gynecology, neurology, and psychiatry. More than 200 expert sub-specialists with extensive clinical experience provide clear, actionable diagnosis and treatment recommendations. Key recommendations are readily accessible in the 778 tables on drug regimens, differential diagnoses, common presenting symptoms, and risk factors. References to current best evidence support the recommendations and lead the reader to scientifically sound research.