This book provides readers with a guide to the use of Digital Twin in manufacturing. It presents a collection of fundamental ideas about sensor electronics and data acquisition, signal and image processing techniques, seamless data communications, artificial intelligence and machine learning for decision making, and explains their necessity for the practical application of Digital Twin in Industry. Providing case studies relevant to the manufacturing processes, systems, and sub-systems, this book is beneficial for both academics and industry professionals within the field of Industry 4.0 and digital manufacturing.