The most comprehensive history of transgender medicine to date, as told by more than forty scholars, physicians, psychologists, and activists from trans, gender-diverse, and allied medical communities. Arriving at a critical moment in the struggle for transgender rights, A History of Transgender Medicine in the United States takes an empathic approach to an embattled subject. Sweeping in scope and deeply personal in nature, this groundbreaking volume traces the development of transgender medicine across three centuries—centering the voices of transgender individuals, debunking myths about gender-affirming care, and empowering readers to grasp the complexities of this evolving field. More than forty contributors—including patients, advocates, physicians, psychologists, and scholars—weave an illuminating, sometimes surprising narrative of collaboration and conflict between trans people and the scientists who have studied and worked with them. An indispensable guide to understanding the current tumult surrounding trans health-care access in the United States, the volume underscores a crucial message: gender diversity is not a new phenomenon but an integral part of our shared human history.