Author Description

<p><b>In-depth monograph presenting innovative radical methodologies in the Brook rearrangement and their utility in organic synthesis</b></p> <p><i>Radical Brook Rearrangement</i> chronicles the evolution of radical Brook rearrangements, synthesizes recent advances in the field, and outlines future research directions. The book focuses on three key reactive intermediates -- &alpha;-siloxy radicals, siloxycarbenes, and silenes -- providing detailed analyses of their generation methods, substrate scope, mechanistic insights, and synthetic applications, along with practical experimental protocols.</p> <p>Readers will find insights on alkoxy radical generation, photocatalytic systems, and the selection of radical/carbene acceptors. This book deliberately focuses on radical processes, excluding anionic pathways.</p> <p>Written by a team of highly qualified researchers in the field, <i>Radical Brook Rearrangement </i>includes information on:</p> <ul> <li>Generation of siloxycarbenes for metal siloxycarbene reaction, with information on aminooxycarbene reactions</li> <li>Generation of siloxycarbenes for nucleophilic addition reaction, covering aldehydes and ketones as electrophiles and other electrophilic reagents</li> <li>Generation of &alpha;-siloxy silyl radicals with (TMS)3SiOH, covering photoredox reactions and metallaphotoredox reactions with (TMS)3SiNHAd</li> <li>Generation of &alpha;-siloxy radicals with &alpha;-silyl alcohol, covering metal-free, metal-catalyzed, photocatalyzed, and electrophotocatalyzed reactions</li> </ul> <p>Containing cutting-edge research discoveries on the subject, <i>Radical Brook Rearrangement</i> is an essential reference for chemists across specializations, materials scientists, and professionals in the pharmaceutical industry.</p>