Mrs. Panda has a warm and affectionate relationship with her little cub friends. The cubs are concerned and rush to help when they see Mrs. Panda lose her balance and tumble down. Mrs Panda has an important role of explaining she has ALS (Lou Gehrig's Disease) in simple terms so the cubs can understand the loss of the body's nerves and power to the muscles. As the cubs express their fears, Mrs. Panda finds a unique way to offer encouragement through her five senses, which are not affected by ALS. Most importantly, Mrs. Panda reaffirms her loving bond with the cubs, who will share a smile forever and ever.