Author Description

"This book comprehensively reviews the role of stem cell therapy against various neurodegenerative disorders. The initial chapters present different neurodegenerative disorders and discuss the application of stem cell therapy for Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington's Disease. Aging and its impact on neurodegenerative disorders are also covered, addressing neuronal dysfunctions with age, neuromuscular dysfunctions like sarcopenia and frailty, and the potential role of stem interventions in aging. The subsequent section provides an overview of the different types of therapies, including cell replacement and neuroprotection. It also covers clinical trials of stem cell therapies for neurodegenerative disorders and discusses the advantages and disadvantages of various stem cell types and delivery methods. Further, the book explores the mechanisms of action, detailing how stem cells induce neural regeneration and repair. It also examines their role in reducing inflammation and oxidative stress, alongside potential risks and safety concerns associated with stem cell therapies. Towards the end, the book presents advanced delivery systems for stem cell therapies, the therapeutic potential of stem cell-derived exosomes and microvesicles in neurodegeneration, preclinical studies in animal models, and the role of organoids in neurodegenerative disorders. This book is useful for researchers and students of neuroscience, neurology, stem cell, pharmaceutical sciences, and biotechnology"-- Provided by publisher.