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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1910 Excerpt:...with temperature, while most of the values to be found for the solubility in cold water and alcohol are only a little more than one-half the quantities indicated by the present determinations, which were made at 25 C. Solubility of citric acid in organic solvents.--The determinations were made, as already described, with the same organic solvents used for benzoic and camphoric acids. Both the hydrated and anhydrous citric acid were used, and it is seen that the latter is the less soluble of the two in all cases. The results are given in Table XVII. An examination of the literature shows that in addition to water and alcohol, results are given for none of the solvents included in the table, except ether. The results quoted for ether are quite variable; thus 100 parts of ether dissolve, according to the II. S. Pharmacopoeia, 5.5 parts of citric acid, 2 parts according to Hager, and 9.1 parts are reported by Beilstein. These variations are easily explained by the fact that the solubility of citric acid is very great in water and in alcohol, and therefore the presence of either of these solvents in the ether used for the determinations would account for the different values reported. A few results obtained by me with ether from a can which had been opened for some time illustrated this point very forcibly. The values were from about 30 to 80 per cent higher than those given in the tables for absolute ether. The figures are not given herewith, however, since the actual composition of the ether was not known, and they therefore have no especial interest. Table No. XVII.--Solubility of citric, acid in teveral organic solvents at 25. SOLUBILITY OF HYDRATED CITRIC ACID. The amounts of citric acid dissolved by the following solvents were too small for estimation: Ben...