Author Description

This book provides a comprehensive overview of hydrolysis mechanisms, their common features, and the importance of hydrolysis mechanisms for modern drug discovery and development efforts. Coverage begins with fundamental mechanisms, then moves to mechanistic features, with a perspective of future mechanistic studies on specific hydrolysis reactions. The discussion of hydrolysis-related drug discovery and development includes catalytic antibodies, prodrugs, hydrolase inhibitors, and protein drugs designed based on the hydrolysis mechanisms. This essential reference offers chemists and related researchers a uniquely multidisciplinary overview of the topic, with implications throughout pharmaceutical science and biochemistry.