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Partial table of contents: FUNDAMENTALS OF LUNG SURFACTANT AND SURFACTANT REPLACEMENT THEORY. The Development of Surfactant Replacement Therapy (D. Shapiro). Pulmonary Surfactant Proteins: Implications for Surfactant Replacement Therapy (J. Whitsett & T. Weaver). Metabolism of Endogenous Surfactant and Exogenous Surfactants Used for Replacement Therapy (A. Jobe). Immunologic Considerations Regarding Exogenous Surfactants (T. Merritt, et al.). CLINICAL ASPECTS OF SURFACTANT REPLACEMENT THERAPY. Surfactant for the Treatment of RDS: Selected Clinical Issues (W. Taeusch, et al.). Artificial Lung Expanding Compound (ALEC): Clinical Experience (C. Morley). Clinical Experience with Calf Lung Surfactant Extract (J. Kendig, et al.). Surfactant Therapy in Adult Respiratory Distress Syndrome and Lung Injury (B. Holm & R. Notter). The Future of Surfactant Replacement Therapy (D. Shapiro).