
This book serves as a reference text in the field of experimental traumatology. Chapters are written by the recognized leaders in each area. The first section covers methodological considerations, including discussion of in vitro and in vivo models; metabolic and hemodynamic factors; anatomical and electrophysiological correlates; and behavioral evaluation. The second section discusses pathophysiological factors including ischemia, ionic changes, immune-inflammatory responses, neurotransmitter/neuromodulatory alterations, effects of lipid metabolism, astroglial responses and molecular mechanisms. The final section reviews treatments including experimental pharmacology, growth factors, regeneration, transplantation and clinical treatment. This book is invaluable to researchers as well as clinicians involved in head or spinal cord injury.
This text investigates the complex pathophysiological mechanisms and therapeutic interventions associated with central nervous system trauma. Edited by Alan I. Faden and Steven K. Salzman, the volume compiles contributions from leading experts in experimental traumatology to establish a comprehensive framework for understanding injury at the cellular and systemic levels. It synthesizes current research on metabolic, anatomical, and molecular responses to head and spinal cord damage to guide both laboratory investigation and clinical practice.
What You Will Find
Experts recognize this volume as a foundational reference for researchers and clinicians specializing in neurotrauma. The text is noted for its technical density and its systematic approach to bridging the gap between experimental laboratory findings and clinical application.
Page Count:
347
Publication Date:
1994-01-15
Publisher:
Oxford University Press
ISBN-10:
0195072308
ISBN-13:
9780195072303
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