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Volume 75 of Advances in Cancer Research continues the series' goal of publishing timely and authoritative reviews in the broad field of cancer research. Graves and Petersen begin the volume with a review of ets proteins and their role in biological specificity. Chapter 2 by Boshoff and Weiss discusses Kaposi's sarcoma and its associated herpesviruses. Chapter 3 by Taipale and colleagues discusses the ways in which the effects of TGF-B can be targeted through its deposition to the extracellular matrix in a latent form. Petersen and colleagues present their research on breast cancer from the phenotypic differentiation standpoint in Chapter 4. The clinical, pathological, and genetic characteristics of hereditary renal carcinoma are reviewed by Zbar and Lerman in Chapter 5. In Chapter 6, Ellem and co-workers discuss the numerous ways in which metastatic cells escape immune killing. Chapter 7 by Kramer et al. Concludes the volume with a discussion on the role of apoptosis via CD95 in liver, colon, and hematopoetic cells.
This volume investigates the current state of molecular and clinical oncology by synthesizing recent findings across diverse sub-disciplines of cancer research. Editor George F. Vande Woude compiles peer-reviewed contributions from specialized researchers to provide a comprehensive update on mechanisms of tumorigenesis, viral associations, and therapeutic targets.
What You Will Find
Scope Limits
Experts recognize this series as a standard reference for researchers requiring high-level summaries of specific oncological developments. Readers frequently note the technical density of the prose, which assumes a foundational understanding of molecular biology and clinical pathology.
Page Count:
282
Publication Date:
1998-08-14
Publisher:
Academic Press
ISBN-10:
0120066750
ISBN-13:
9780120066759
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