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Volume 71 of Advances in Cancer Research begins with Morgan and Kastan presenting data on the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to targets for improved cancer therapie
This volume investigates the molecular mechanisms governing cell cycle progression and apoptosis in response to DNA damage. The text compiles research findings regarding the roles of p53 and ATM proteins, evaluating how these biological pathways function as critical checkpoints. By analyzing these cellular responses, the contributors aim to identify potential targets for the development of improved cancer therapies.
What You Will Find
Scope Limits
Experts recognize this series as a standard reference for researchers focusing on the molecular biology of oncology. Readers frequently note the high level of technical density required to engage with the presented experimental data.
Page Count:
307
Publication Date:
1989-11-11
Publisher:
Academic Press
ISBN-10:
012006653X
ISBN-13:
9780120066537
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