
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.
This volume investigates the integration of genomic methodologies into the processes of cancer drug discovery and clinical development. Edited by George F. Vande Woude, the text compiles contributions from leading researchers to address how genomic and proteomic data can accelerate the identification of therapeutic targets and the validation of biomarkers. The work serves as a thematic bridge between basic molecular biology and the practical requirements of pharmaceutical development.
What You Will Find
Scope Limits
Experts recognize this volume as a significant reference for researchers transitioning from academic discovery to translational oncology. Readers frequently note the technical density of the prose, which assumes a high level of prior knowledge in molecular biology and pharmacology.
Page Count:
432
Publication Date:
2007-01-02
Publisher:
Academic Press
ISBN-10:
0120066963
ISBN-13:
9780120066964
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