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IARC and the NIH were joined by the French Ministry of the Environment in the development of a program to establish and validate methods for the decontamination of wastes contaminated by chemical carcinogens and the treatment of spillages with such compounds. Eight volumes have been published dealing with aflatoxins, nitrosamines, polycyclic aromatic hydrocarbons, hydrazines, nitrosamides, haloethers, aromatic amines and a series of antineoplastic agents (IARC Scientific Publications Nos. 37, 43,49, 54, 55, 61, 64 and 73). In this volume, the ninth of the series, methods of degradation are presented for four commonly investigated mycotoxins: ochratoxin A, citrinin, patulin, and sterigmatocystin. In view of new findings, a re-investigation has also been performed for aflatoxins and these compounds have been tested in one of the methods. The five methods presented can be applied to various waste categories and three of them to spillage treatment. Chemical and biological information concerning these compounds is also presented in an appendix to these methods.
This volume investigates the development and validation of standardized chemical degradation methods for the safe disposal of N-nitroso compounds in laboratory settings. The International Agency for Research on Cancer (IARC) and the National Institutes of Health (NIH) collaborated to establish rigorous protocols for neutralizing hazardous chemical waste. The text provides a technical framework for laboratory personnel to mitigate risks associated with the handling and disposal of specific carcinogenic agents.
What You Will Find
Experts recognize this publication as a foundational technical manual for institutional safety officers and laboratory managers. The text is noted for its high level of procedural density and its reliance on standardized empirical validation methods.
Page Count:
82
Publication Date:
1984-12-20
Publisher:
Oxford University Press
ISBN-10:
0197230431
ISBN-13:
9780197230435
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