Kamala Khan, the super-powered teenager known as Ms. Marvel, finds her world expanding as she encounters iconic Marvel heroes and faces universe-altering threats. Driven by her desire to do good and protect her city, Kamala navigates complex relationships with mentors like Captain Marvel and allies such as Wolverine and Spider-Man, while also uncovering her own Inhuman heritage and joining new teams like the Avengers and Champions. The narrative framework is that of a collected edition, weaving together various comic book issues that highlight Ms. Marvel's growing presence and impact across the Marvel Universe.

This collection showcases Ms. Marvel's burgeoning role within the wider Marvel Universe, highlighting her interactions with established heroes and her own developing legacy. The stories emphasize her youthful energy and heroic spirit as she teams up with figures like Wolverine, Spider-Man, and Captain Marvel, while also exploring her unique Inhuman heritage. The inclusion of her joining major teams like the Avengers and the Champions demonstrates her growing significance among Earth's Mightiest Heroes. The narrative arc suggests a focus on Kamala Khan's personal growth and her impact on the Marvel continuity, positioning her as a key figure for a new generation of readers.