The Thing's cosmic adventures escalate as he encounters a powerful, resurrected cosmic entity and joins forces with unlikely allies against world-threatening forces. The Thing, alongside Starhawk, discovers the re-emergence of a being previously thought dead, initiating a saga that involves Moondragon, the High Evolutionary, and Adam Warlock. This cosmic conflict is paralleled by an underwater battle against the Serpent Squad, featuring Stingray, Scarlet Witch, and Triton. The volume further explores team-ups with Hyperion and the Angel, leading to a major confrontation with Maelstrom, and concludes with a prehistoric battle and a team-up against the Puppet Master.

This collection is part of the Marvel Masterworks line, which is known for presenting classic Marvel comics in high-quality hardcover editions. The stories within this volume, originally published in the late 1970s, showcase the Thing in a variety of team-up scenarios, a hallmark of the Marvel Two-In-One title. Readers familiar with this era of Marvel comics can expect a blend of cosmic adventures, street-level threats, and classic superhero team-ups. The inclusion of major cosmic characters and villains suggests a narrative scope that appeals to long-time fans of the Marvel Universe.