A cosmic corpse unleashes an interstellar plague that transforms Earth's heroes into ravenous zombies. When the body of Galactus is discovered at the edge of the solar system, the Avengers, X-Men, and Fantastic Four investigate, only to find it harbors a terrifying contagion. This plague rapidly infects Earth's Mightiest Heroes, turning them into flesh-eating undead abominations. The remaining defenders must now fight their former friends and family, desperately seeking a way to survive and protect the planet from an infestation that has already consumed half the known universe.

The premise of Marvel Zombies: Resurrection sets up a high-stakes, action-packed horror narrative within the Marvel Universe. The focus on beloved heroes turned into monstrous threats suggests a story that explores themes of survival, loss, and the grim consequences of a widespread apocalypse. The narrative framework, as indicated by the description, likely centers on the desperate efforts of a few remaining heroes to combat an overwhelming, familiar enemy. The inclusion of Spider-Man's personal promise adds a layer of character-driven conflict to the broader survival struggle.