Author Description

Key molecular aspects of disease, especially in relevance to targeted therapy/personalized medicine, will be addressed Cancer research has meant important development in the molecular mechanism of cancer and the implications of these mechanisms in developing targeted therapies for the treatment of many cancers. The skin is no exception to these developments, and this has been particularly crucial in cancers like melanoma. The chapter on melanoma has been extensively revised in order to cover these important subjects.The introduction of numerous new therapies in the last decade particularly with the introduction of biologics for the treatment of inflammatory disease such as psoriasis and targeted therapies for the management of cancers has meant the emergence of a growing number of newly observed side effects that often affect the skin. This means that the chapter on drug eruptions will have to be revised extensively to account for this important development in the field of therapeutics. New developments in Immunohistochemistry (IHC) have resulted in the availability of new antigens/antibodies to diagnose tumor specimens, to determine staging and grading of a malignant tumor and to determine the origin of a metastasis in order to find the site of the primary tumor. This book will help keep the user stay current with the latest diagnostic tumor markers to assist in daily sign-out.