Artificial intelligence has become an indispensible part of our lives in recent years, affecting all aspects from business and leisure to transport and health care. This book presents the proceedings of the 23rd edition of the International Conference of the Catalan Association for Artificial Intelligence (CCIA), an annual event that serves as a meeting point for researchers in Artificial Intelligence in the area of the Catalan speaking territories and from around the world. The 2021 edition was held online as a virtual conference from 20 - 22 October 2021 due to the COVID-19 pandemic. The book contains 42 long papers and 9 short papers, carefully reviewed and selected. The papers cover all aspects of artificial intelligence and are divided under six section headings: combinatorial problem solving and logics for artificial intelligence; sentiment analysis and tekst analysis; data science and decision support systems; machine learning; computer vision; and explainability and argumentation. Abstracts of the 2 invited talks delivered at the conference by Prof. Patty Kostkova and Prof. João Marques-Silva are also included. Offering a state of the art overview of the subject from a regional perspective, the book will be of interest to all those working in the field of artificial intelligence.