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Most people are familiar with the fact that diamond and graphite are both composed only of carbon; yet they have very different properties which result from the very different structures of the two solids - they are polymorphs of carbon. Understanding the relationship between the structures and the properties of materials is of fundamental importance in developing and producing new materials with improved or new properties. The existence of polymorphic systems allows the direct study of the connection between structures and properties. This book provides grounding on the fundamental structural and energetic basis for polymorphism, the preparation and characterization of polymorphic substances and its importance in the specific areas of pharmaceuticals, pigments and high energy (explosive) materials. The closing chapter describes the intellectual property implications and some of the precedent patent litigations in which polymorphism has played a central role. The book contains over 2500 references to provide a ready entry into the relevant literature.
This text investigates the fundamental structural and energetic principles governing polymorphism in molecular crystals and its practical implications across various industrial sectors. Joel Bernstein, a recognized authority in the field, synthesizes decades of research to explain how identical chemical compositions can manifest as distinct solid-state structures with varying physical properties. The book provides a rigorous framework for understanding the preparation, characterization, and industrial relevance of these systems, bridging the gap between theoretical crystallography and applied material development.
What You Will Find
Experts and researchers in the field of crystallography identify this work as a foundational reference for understanding the complexities of solid-state chemistry. Readers frequently note the academic density of the prose, which serves as an exhaustive resource for both students and professionals working in material science and patent law.
Page Count:
608
Publication Date:
2023-07-27
Publisher:
Oxford University Press
ISBN-10:
0198877358
ISBN-13:
9780198877356
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