This book investigates the ethical and legal framework surrounding human experimentation, focusing on the critical concept of informed consent. George J. Annas, a legal scholar specializing in health law and bioethics, examines the historical context and evolving standards that govern medical research involving human subjects. The work presents a detailed analysis of the principles and practices necessary to ensure that participants in research fully understand the risks and benefits before agreeing to take part.

This seminal work by George J. Annas is recognized for its thorough examination of the legal and ethical dimensions of informed consent in human experimentation. It provides a foundational understanding for students, researchers, and legal professionals navigating the complexities of medical research ethics. The book is cited for its clear articulation of principles and its historical perspective on the development of ethical guidelines in the field.