This book chronicles the scientific advancements in understanding malaria biochemistry over a hundred-year period. The author, Irwin W. Sherman, draws upon his extensive experience in the field to present a comprehensive overview of the key discoveries, challenges, and evolving methodologies in malaria biochemistry research. It examines the molecular mechanisms of the parasite, its interaction with the host, and the biochemical basis of drug resistance. The text aims to provide a historical perspective on the scientific journey to combat this persistent disease.

This work is recognized as a significant contribution to the historical and scientific literature on malaria. It is likely to be valued by researchers, historians of science, and public health professionals for its detailed account of a century of biochemical investigation into this disease. The book's comprehensive scope and the author's expertise suggest it serves as both a historical record and a foundational text for understanding current and future research efforts in malaria biochemistry.