The Incredible Hulks face an existential threat that could unravel their very existence. The team, comprised of various Hulk personas, must confront a new, powerful enemy that targets their unique physiology and mental states. Their struggle is not only against an external force but also against their own internal conflicts and the potential for their powers to consume them, all while navigating a world that fears and misunderstands them.

The Incredible Hulks series is generally well-received by fans of the characters, praised for its intricate plotting and deep dive into the psyches of the Hulk personas. Critics often highlight Greg Pak's ability to balance intense action with compelling character drama, exploring the complexities of rage and identity. The narrative is noted for its ambitious scope, pushing the boundaries of what it means to be a Hulk. This run is considered a significant contribution to the Hulk mythos, offering a fresh perspective on familiar characters.