Mark Twain, presumed dead for a century, returns to recount his continued life and adventures. Aided by humorist Michael Kupperman, Twain details his experiences from World War I through the present day, covering a vast array of unconventional careers including ad man, astronaut, hypnotist, and porn star. He recounts his encounters with numerous historical figures, offering never-before-told stories from the 20th and 21st centuries.

The premise of Mark Twain surviving for a century and detailing modern history through his unique lens offers a rich ground for satire and humor. The collaboration with Michael Kupperman suggests a blend of Twain's distinctive voice with contemporary comedic sensibilities. This work likely appeals to readers who enjoy historical fiction with a speculative twist and a strong dose of wit. The narrative structure, framed as an autobiography, allows for a personal and often absurd perspective on significant historical periods and figures.