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This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders.Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format.This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.
This text investigates how recent breakthroughs in genetics and neurobiology can be translated into targeted clinical interventions for neurodevelopmental disorders. Authors Randi J. Hagerman and Robert L. Hendren synthesize complex molecular data and animal model research to provide a practical framework for clinicians. The book bridges the gap between laboratory discovery and patient care, offering a comprehensive overview of how specific biological mechanisms inform modern treatment strategies.
What You Will Find
Experts recognize this volume as a foundational resource for clinicians seeking to apply current genetic research to daily practice. Readers frequently note the clarity with which the authors translate dense neurobiological data into actionable clinical insights.
Page Count:
400
Publication Date:
2014-01-01
Publisher:
Oxford University Press
ISBN-10:
0199378886
ISBN-13:
9780199378883
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