
Recent developments have revealed that proteins can undergo a diverse range of modifications by lipids which can dramatically effect their structural and functional properties. These modifications include acylation, isoprenylation, and the attachment of glycolipid. Written by acknowledged experts in the field, this unique guide describes the latest biochemical, cell biological, and molecular biological techniques being used in this rapidly expanding area. The book discusses lipid modifications of proteins which play important roles in cellular signalling, protein targeting and cellular growth and differentiation. Detailed protocols are provided for all the key techniques, and the relevant background material is included. The book will be an essential manual for a wide range of scientists studying the modification of protein by lipids, including membrane and protein biochemists, cell biologists, immunologists, bacteriologists, parasitologists, and virologists.
This volume investigates the biochemical mechanisms and functional consequences of protein lipid modification, addressing how these alterations influence cellular signaling and protein localization. Edited by A. J. Turner and N. M. Hooper, the text synthesizes contributions from experts to provide a comprehensive framework for understanding acylation, isoprenylation, and glycolipid attachment. The authors integrate theoretical background with rigorous experimental protocols to assist researchers in navigating this complex area of molecular biology.
What You Will Find
Experts recognize this work as a foundational laboratory manual for researchers investigating post-translational protein modifications. Readers frequently note the technical density of the protocols, which serve as a reliable reference for practitioners in molecular and cellular biology.
Page Count:
312
Publication Date:
1992-08-27
Publisher:
IRL Press
ISBN-10:
0199632731
ISBN-13:
9780199632732
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