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Proceedings summarizing the results of the XXVII-th International Open Science Conference "Modern informatization problems in economics and safety" (MIP-2022'ES), held in November 2021 - January 2022. It contains information within the following areas: information systems and their applications, information systems in economics.Data gathered within collected papers may be useful to researchers and engineering technicians, whose work involves various aspects of modern society informatization, as well as to postgraduates and students studying subjects related to informatics and computer engineering.