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The Advances In Biotechnology And Molecular Biology Over Recent Years Have Resulted In A Large Number Of Novel Molecules With The Potential To Revolutionize The Treatment And Prevention Of Disease. However, Such Potential Is Severely Compromised By Significant Obstacles To Delivery Of These Drugs In Vivo. These Obstacles Are Often So Great That Effective Drug Delivery And Targeting Is Now Recognized As The Key To Effective Development Of Many Therapeutics. Advanced Drug Delivery And Targeting Can Offer Significant Advantages To Conventional Drugs, Such As Increased Efficiency, Convenience, And The Potential For Line Extensions And Market Expansion. An Accessible And Easy-to-read Textbook, Drug Delivery And Targeting For Pharmacists And Pharmaceutical Scientists Is The First Book To Provide A Comprehensive Introduction To The Principles Of Advanced Drug Delivery And Targeting, Their Current Applications And Potential Future Developments, Including: *methods To Optimize Therapeutic Efficacy, And The Related Commercial Implications *difficulties With Drug Absorption, Unwanted Distribution And Premature Inactivation / Elimination *attempts To Minimize Toxicity Or Alter Immunogenicity *methods To Achieve Rate-controlled Drug Release And Effective Drug Targeting *novel And Established Routes Of Delivery *use Of New Generation Technologies Such As Biosensors, Microchips, Stimuli-sensitive Hydrogels And Plasmid-based Gene Therapy This Volume Is Indispensable For Pharmaceutical Students, Scientists And Researchers.
This book investigates the critical challenges and methodologies associated with the effective delivery and targeting of novel therapeutic molecules in vivo. The authors, Andrew W. Lloyd, Anya M. Hillery, and James Swarbrick, leverage their expertise in pharmaceutical sciences to provide a structured framework for understanding how advanced delivery systems can overcome biological barriers. The text synthesizes current research on drug absorption, distribution, and elimination to offer a comprehensive overview of how to optimize therapeutic efficacy while minimizing systemic toxicity.
What You Will Find
Experts and educators recognize this volume as a foundational introductory text for students and researchers entering the field of pharmaceutical development. Readers frequently note the clarity of the prose, which effectively bridges the gap between complex molecular biology and practical clinical application.
Page Count:
496
Publication Date:
2016-01-01
Publisher:
Taylor & Francis Group
ISBN-10:
0203302761
ISBN-13:
9780203302767
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