A woman's alien consciousness struggles to adapt to a human body and the complexities of human relationships, especially as her physical form begins to reject her alien mind. Aliena, an alien entity inhabiting a human host, must navigate the intricacies of human society and the physical limitations of her borrowed form. Her primary challenge arises when her body's immune system begins to reject the alien brain, necessitating a replacement. This biological crisis forces both Aliena and the man who loves her to confront the escalating difficulties in maintaining the facade of a normal marriage and family life.

The premise of Aliena suggests a narrative that delves into the complexities of identity and belonging, exploring the challenges of an alien consciousness attempting to integrate into human society. The story appears to focus on the intimate struggles of maintaining relationships and family structures under extraordinary circumstances, particularly when faced with biological incompatibility. The narrative likely examines the emotional and psychological toll of such an existence on both the alien and those close to her. The core conflict seems to stem from the tension between the alien's nature and the human form, and the desperate measures required to preserve a semblance of normalcy.