The book chronicles the pioneering achievements of Elizabeth Blackwell and Elizabeth Garrett Anderson, the first women to become qualified physicians in their respective countries. It details their struggles against societal barriers and institutional prejudice in the 19th century, highlighting their determination to pursue medical careers and establish practices that would pave the way for future generations of women in medicine.

This book is presented as an educational resource, likely aimed at younger readers or those new to the subject, given its inclusion in a 'Collins Big Cat' series. The focus is on presenting the historical achievements of two significant figures in medicine. The narrative is expected to be informative and accessible, highlighting the challenges and triumphs of these pioneering women.