This book documents the latest findings on the genetic and immunological links to narcolepsy, focusing on the strong association with HLA-DR2, Dw2, and DPwl. It synthesizes recent observations on immunological aspects, DNA typings, and other genetic markers, alongside investigations into the molecular biology of a canine animal model. The work also details extensive clinical studies conducted in Japan on hundreds of narcolepsy patients and presents the potential significance of advancing HLA and DNA research for developing DNA diagnostics for the disorder.

This book compiles significant research on the genetic underpinnings of narcolepsy, particularly focusing on Human Leukocyte Antigen (HLA) associations. The detailed clinical studies from Japan and the exploration of animal models suggest a thorough, albeit specialized, scientific inquiry. The work appears to be aimed at researchers and clinicians actively involved in sleep disorders and human genetics, offering a deep dive into specific genetic markers and diagnostic potential. Its focus on the late 1980s research landscape positions it as a historical reference for the field's progression.