This volume investigates the state of histocompatibility and immunogenetics research as of 1991, specifically focusing on the standardization of HLA typing and the analysis of genetic diversity. The text compiles the findings of the eleventh International Histocompatibility Workshop and Conference, bringing together global experts to present data on human leukocyte antigen (HLA) systems. It serves as a comprehensive record of the methodologies, statistical analyses, and clinical observations established by the international scientific community during this period.

Experts recognize this volume as a foundational archival record for the evolution of HLA nomenclature and diagnostic standards. Researchers frequently consult these proceedings to understand the historical baseline of immunogenetic data and the collaborative methodologies used in early 1990s clinical studies.