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The neuropathology of schizophrenia is one of the most controversial areas of research in psychiatry; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a much needed, balanced, comprehensive and up-to-date overview of this rapidly moving field. It starts by describing the findings derived from new imaging techniques and histological studies, focusing specifically on the morphology, arrangement and connectivity of the neurons making up the cortical cytoarchitecture, a feature thought to be central to understanding the pathology. This is followed by critical appraisal of the various interpretations placed upon these findings, such as the neurodevelopmental hypothesis. Finally, there are chapters considering the conceptual and methodological problems affecting the subject. This is a timely and unique book on this classic and controversial issue, with contributions from many of the leading international experts in the field.
This book investigates the complex neuropathological underpinnings of schizophrenia by synthesizing two decades of research to clarify the biological basis of the disorder. Authors Gareth Roberts and Paul J. Harrison, both established experts in psychiatric research, curate a collection of contributions from international specialists to evaluate the current state of the field. The text moves beyond simple observation to provide a critical framework for interpreting neuroimaging and histological data within the context of modern psychiatric theory.
What You Will Find
Scope Limits
Experts recognize this volume as a rigorous synthesis of the biological evidence surrounding schizophrenia. Readers frequently note the academic density of the prose, which is intended for researchers and clinicians seeking a comprehensive overview of the field's progress.
Page Count:
374
Publication Date:
2000-10-15
Publisher:
Oxford University Press
ISBN-10:
0192629077
ISBN-13:
9780192629074
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