The new edition of the Oxford Handbook of Clinical Medicine is the best yet. It has been completely reset in more readable type, it contains more diagrams and boxes and completely new chapters. But, most important, has been the meticulous updating of each page with the best that evidence-based medicine can offer. Concise, readable, and authoritative, the text is a model of everything a Handbook should be. But it is more than model -- it is the one trusted friend found in white coat pockets the world over - now reborn in new colours with a new full-colour plate section and a wealth of new material. This Handbook is associated with its own web site, and widely acclaimed updateable electronic version (the Oxford Clinical Mentor). Thus Oxford University Press offers a complete system for updateable clinical information. New topics for this edition include: surviving house jobs, medical ethics, assessing the locomotor system, the role of jargon, facial pain, walking difficulty, help for patients with Alzheimer's and their carers, fundoplation, somatization, exotic infections, what every doctor needs to know about HIV, anti-HIV drugs in detail, numbers-needed-to-treat, screening, cardiovascular health, Candida in ITU, posteria myocardial infarction, atheroma and the mechanism and action of statin drugs.