This text investigates the core mathematical principles underpinning biostatistical inference. It is designed for a one-semester graduate course, requiring a foundation in undergraduate calculus and prior exposure to basic statistical or biostatistical methods. The book aims to provide students with a rigorous understanding of the theoretical underpinnings necessary for advanced study and application in the field.

The book is presented as a textbook for a specific graduate-level course, indicating its intended audience is students with a solid mathematical background. Its focus on mathematical foundations suggests a rigorous and theoretical approach to biostatistics, likely appealing to those seeking a deep understanding of the subject's underpinnings rather than practical application alone. The annotation implies it serves as a foundational text for further study in the field.