
As an Amazon Associate and affiliate partner, Menrva Books earns from qualifying purchases. Learn more
Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
This book investigates the critical role of the cellular protein quality control system in the development and progression of neurodegenerative disorders. It explores how factors such as aging, oxidative stress, and genetic inconsistencies can impair this system, leading to protein misfolding and aggregation, which are hallmarks of diseases like Alzheimer's and Parkinson's. The text examines potential therapeutic strategies that target protein quality control mechanisms as a means to halt neurodegeneration, offering insights into molecular chaperones, stress signaling, and other relevant pathways.
The book is designed for a specialized audience, including neurobiologists, medical professionals, and researchers, offering a comprehensive overview of protein quality control in neurodegenerative disorders. Its focus on potential therapeutic strategies suggests an emphasis on translational research and clinical applications. The detailed exploration of molecular mechanisms and contributing factors indicates a text that is likely to be dense and informative, serving as a valuable resource for those engaged in advanced study and practice within the field.
Page Count:
260
Publication Date:
2020-01-01
Publisher:
Medical Information Science Reference
ISBN-10:
1799813177
ISBN-13:
9781799813170
No comments yet. Be the first to share your thoughts!