This text investigates the physiological mechanisms that allow nematodes to survive and thrive across diverse ecological niches, including parasitic and free-living environments. D. L. Lee, a specialist in helminthology, synthesizes experimental data and morphological observations to explain how these organisms maintain homeostasis. The book provides a structured framework for understanding the internal systems of nematodes, focusing on how their unique anatomy facilitates movement, digestion, and reproduction.

Experts recognize this work as a foundational text for students and researchers in nematology and parasitology. Readers frequently note the technical density of the prose, which assumes a solid background in biological sciences.