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This book highlights the genomic findings, observations, and analysis of DNA/RNA sequences and protein structure of the dreadful virus of this decade- COVID-19. The Corona group of viruses though known species, the strain that caused the Pandemic of 2019 is a completely new strain, belonging to the same corona family with a novel genetic make-up. This makes it a new pathogen which is causing the current outbreak leaving the global scientific community clueless of any therapeutic breakthrough. NCOV enjoys life threatening pathogenicity with mysterious genetic annotations. This book details and offers insights into its viral genetic arrangement, Virulence factors, probable mutations leading to the evolution of this new strain and more. It contains chapters on Virus evolutionary status and Genetic makeup leading to its pathogenicity which can be a new insight in understanding the nature of this clever microorganism and can pave way to the development of new drugs and Vaccinesor a novel diagnostic approach for the early prognosis of the disease. A dedicated chapter on annotation of NCOV-19 virulence genes, translation of the genes to protein product, annotation of the antigenic sites on these proteins is also included. In all, this brief is a complete genomic annotation insight of NCOV-19 using AI, Data analytics and Bioinformatics analysis. In the current situation, this book is an extensive preliminary resource for Medical practitioners, Researchers, Academicians, Scientists, Biochemists, Bioinformaticians and other professionals interested in understanding the genetics of Novel Coronavirus 19, the best possible drug targets, ideal vaccine candidates and novel prognostic and diagnostic biomarkers.
This book investigates the genetic makeup and potential therapeutic avenues for the novel coronavirus (COVID-19).
The authors, a team of researchers including Ajit Kumar Saxena and Amita Kashyap, present a detailed genomic analysis of the virus responsible for the 2019 pandemic. Drawing on findings related to DNA/RNA sequences and protein structures, the book explores the virus's genetic arrangement, virulence factors, and potential mutations. It aims to provide insights into the evolution and pathogenicity of this new strain, offering a foundation for the development of new drugs, vaccines, and diagnostic approaches.
This book is positioned as a preliminary resource for medical practitioners, researchers, academicians, scientists, biochemists, and bioinformaticians interested in the genetics of Novel Coronavirus 19. The content focuses on identifying potential drug targets, ideal vaccine candidates, and novel prognostic and diagnostic biomarkers based on genomic insights. The authors' approach utilizes advanced computational methods to analyze the virus's genetic structure and predict its behavior and vulnerabilities.
Page Count:
78
Publication Date:
2020-09-27
Publisher:
Springer Nature Singapore
ISBN-10:
9811579172
ISBN-13:
9789811579172
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