This book investigates the most significant, unresolved questions currently facing the field of systems neuroscience. Edited by J. Leo van Hemmen and Terrence J. Sejnowski, the text compiles contributions from twenty-three prominent experts who each articulate a singular, critical problem within their respective sub-disciplines. The collection functions as a structured inquiry into the brain's complexity, ranging from evolutionary biology to the nature of subjective experience.

Experts recognize this volume as a valuable reference for identifying the primary challenges that define modern systems neuroscience. Readers frequently note that the independent nature of the chapters allows for flexible study, making it a useful resource for both specialists and those seeking a broad overview of the field's current trajectory.