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Since the 1960s we have learned that cardiovascular complications and diabetes mellitus are closely intertwined: type 2 diabetes increases the likelihood of hypertension, hyperlipidemia, and accelerated vascular disease. Thus the growing pandemic of diabetes worldwide is responsible for increasing death and disability from atherosclerotic vascular disease, the number one cause of death today. This publication spells out the enormity of the problem and the demographic forces at play. In the first part of the book the fundamental mechanisms responsible for vascular involvement in diabetes at the genetic, molecular, tissue, organ and organismal levels are described. The second part provides a detailed description of the various clinical aspects and the currently available therapeutic and preventive measures for diabetes, such as lifestyle changes, angiotensin II receptor blockers, biguanides and fibrates.
The growing global pandemic of diabetes mellitus is inextricably linked to cardiovascular complications, driving an increase in death and disability from atherosclerotic vascular disease. This book details the profound connection between diabetes and vascular health, exploring the demographic forces contributing to this crisis. It examines the fundamental mechanisms underlying vascular involvement in diabetes, from genetic and molecular levels to tissue, organ, and organismal impacts. The second part focuses on clinical manifestations and current therapeutic strategies, including lifestyle modifications and pharmacological interventions.
The book addresses the critical and escalating issue of cardiovascular complications in diabetes, a leading cause of mortality. It outlines the scientific basis for this link, exploring mechanisms across multiple biological scales. The text also provides a comprehensive review of clinical management strategies, offering insights into both lifestyle and pharmacological interventions. This work serves as a detailed resource for understanding and combating the vascular sequelae of diabetes.
Page Count:
814
Publication Date:
2005-01-01
ISBN-10:
3805579624
ISBN-13:
9783805579629
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