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Basement membranes are thin, sheet-like layers of extracellular matrix that serve as a crucial interface between cells and their environment. They are found underlying all epithelial and endothelial cells, surrounding muscle and nerve cells, and forming the glomerular filtration barrier in the kidney. Basement membranes play vital roles in cell adhesion, differentiation, migration, and tissue organization. This book provides a comprehensive overview of the structure, composition, biosynthesis, and function of basement membranes, as well as their involvement in various pathological conditions. It is intended for researchers, graduate students, and clinicians interested in the field of extracellular matrix biology.
The Basement Membrane: A Comprehensive Biological Overview. This book delves into the intricate structure and function of basement membranes, essential extracellular matrix components found in virtually all tissues. It examines their critical roles in cell adhesion, differentiation, migration, and tissue organization, drawing upon decades of research. The work synthesizes current knowledge on the molecular composition, biogenesis, and pathological implications of these vital structures.
The Authority Perspective: This text is recognized as a foundational reference for researchers and advanced students in cell biology, histology, and biochemistry. Its comprehensive scope and detailed molecular analysis make it an authoritative resource for understanding the complex roles of basement membranes in health and disease. The work is noted for its rigorous scientific approach and its synthesis of a vast body of literature.
Page Count:
427
Publication Date:
2005-01-01
ISBN-10:
0121533565
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