This book investigates the complex mechanisms of drug-drug interactions (DDIs) mediated by drug-metabolizing enzymes and drug transporters. It provides a comprehensive overview of the current understanding of how these biological components influence drug efficacy and safety, drawing on extensive research and clinical data.

This specialized text is recognized within the pharmaceutical and clinical research communities for its in-depth coverage of enzyme- and transporter-based drug-drug interactions. It is valued for its detailed scientific explanations and its focus on practical applications in drug development and patient care. The book serves as a critical resource for pharmacologists, toxicologists, and clinicians seeking to understand and mitigate the risks associated with drug combinations.