An FBI agent hunting a supernatural killer in Chicago must team up with a private investigator and his unusual associates to stop a centuries-old evil. Jackie Rutledge, an FBI agent accustomed to the city's dark underbelly, finds herself facing a case that transcends the ordinary: victims are brutally drained of blood, evidence disappears, and panic grips the city. To combat this inhuman power, she and her psychic partner, Laurel, must rely on the help of private investigator Nick Anderson and his team, which includes a ghost and a vampire. As Jackie delves deeper, she uncovers Nick's hidden secrets and realizes their investigation has entangled them in a vengeful conflict spanning centuries against a malevolent force.

The premise suggests a fast-paced urban fantasy thriller with a blend of supernatural investigation and noir elements. The inclusion of a psychic partner and a PI with an immortal team points to a narrative that explores the intersection of the mundane and the paranormal in a gritty urban setting. The conflict reaching back centuries indicates a deep mythology and a significant threat that requires more than conventional detective work to overcome. The description implies a focus on action, mystery, and the personal stakes involved for the protagonists as they confront ancient evil.