The Unfolded Protein Response (UPR) is a critical cellular mechanism for maintaining homeostasis under conditions of endoplasmic reticulum (ER) stress. This book investigates the intricate signaling pathways, molecular players, and physiological consequences of the UPR. It explores how cells detect and respond to the accumulation of misfolded proteins, and the implications of UPR dysregulation in various diseases.

This volume is recognized as a comprehensive resource for researchers and advanced students in cell biology and molecular medicine. It synthesizes current knowledge on the unfolded protein response, providing a detailed overview of its molecular mechanisms and physiological relevance. The book is structured to offer both foundational understanding and insights into disease-related aspects of UPR. Its authority stems from the collective expertise of contributors in the field.