This volume investigates the complex mechanisms by which presynaptic receptors modulate neurotransmitter release. It explores the fundamental question of autoregulation, examining how neurons control their own signaling output. The book syntheses research on various neurotransmitter systems and their corresponding presynaptic receptors, detailing the molecular and physiological processes involved.

This collection of papers, originating from a New York Academy of Sciences conference, presents a focused exploration of presynaptic receptor function. The content is expected to be highly technical, suitable for researchers and advanced students in neuroscience and pharmacology. The compilation likely offers a snapshot of the state of research in the early 1990s regarding neurotransmitter release modulation.