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Depression is a major cause of morbidity throughout the world. Given that between 8 and 12% of the population (in most countries) will suffer from depression at some point in their lives, it is clearly a significant public health problem. As our knowledge of this illness has expanded in recent years, it has become clear that depression can no longer be viewed as a simple disorder of the brain. It has to be seen as a series of behavioural and biological changes that span mind, brain, genes, and body--indeed, affecting both psychological and physical health.This book brings together world leaders in research on depression to discuss, for the first time, in an interdisciplinary setting, both classical and innovative ideas to understand this devastating disorder. It presents neurobiological, psyschological, genetic, and evolutionary models with a particular emphasis on the mechanisms linking the brain to the endocrine and the immune systems, and therefore, linking depression to physical health.Opening with a powerful, personal account of depression that conveys something of the all-consuming, debilitating nature of this illness, the book then presents cutting-edge research from those at the frontier of work in this area. The book is valuable for all those in the brain sciences seeking a state-of-the-art review of this global problem.
This book investigates the complex, multi-faceted nature of depression by examining it as a systemic disorder that integrates biological, psychological, and evolutionary mechanisms. The authors, a team of leading researchers in brain science, argue that depression cannot be reduced to a simple brain chemistry imbalance. Instead, they present a translational framework that connects genetic, endocrine, and immune system responses to explain how the condition manifests across the entire human body.
What You Will Find
Experts recognize this volume as a comprehensive resource for professionals and researchers in the brain sciences. Readers frequently note the academic density of the prose, which serves as a rigorous state-of-the-art review for those seeking to understand the systemic nature of the illness.
Page Count:
304
Publication Date:
2009-09-14
Publisher:
Oxford University Press
ISBN-10:
0199533075
ISBN-13:
9780199533077
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