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Patients are beginning to benefit from antibody based, cellular and vaccine approaches that are effective against genetically diverse and therapy-resistance cancers. BCG immunotherapy is now being used as a first line treatment for human bladder cancer and the introduction of prophylactic vaccination against Hepatitis B and HPV cancers is starting to show positive results. Following recent FDA approval for a vaccination against prostate cancer, and optimistic results in clinical trials for a vaccine targeting cancer antigens in lung cancer, cancer immunotherapy is now significantly impacting patient clinical management.Tumor Immunology and Immunotherapy provides an up-to-date and comprehensive account of cancer immunity and immunotherapy. It discusses our adaptive and innate immunity to cancer, the mechanisms underpinning our immune response, current approaches to cancer immunotherapy, and how tumour and host responses can circumvent effective anti-cancer immunity.The book examines recent results, publications and current areas of interest including 'immune editing' and the specific issues that are affecting the research and development of vaccines, providing insight into how these problems may be overcome, as viewed by world leaders in the field. Tumor Immunology and Immunotherapy will appeal to clinicians working in oncology and cancer immunotherapy, and research scientists including PhD and masters students, post-doctoral researchers and senior investigators.
This text investigates the mechanisms of cancer immunity and the clinical application of immunotherapy in the treatment of genetically diverse and therapy-resistant malignancies. Robert C. Rees, a recognized expert in the field, synthesizes current research on adaptive and innate immune responses to provide a framework for understanding how tumor-host interactions influence clinical outcomes. The book evaluates the efficacy of existing vaccine and antibody-based therapies while addressing the biological hurdles that prevent effective anti-cancer immune responses.
What You Will Find
Experts and researchers identify this work as a comprehensive resource for clinicians and investigators seeking to understand the intersection of immunology and cancer management. Readers frequently note the technical density of the prose, which is tailored specifically for an audience of oncology professionals and advanced research students.
Page Count:
480
Publication Date:
2014-07-29
Publisher:
Oxford University Press
ISBN-10:
0199676860
ISBN-13:
9780199676866
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