This book investigates the biological and psychological necessity of pleasure, arguing that positive emotional states are essential components of human health rather than mere luxuries. The authors, David Sobel and Robert Ornstein, utilize research from the fields of immunobiology, genetics, and behavioral psychology to construct a framework for understanding how sensory and emotional satisfaction impacts physical longevity. They contend that by consciously cultivating positive attitudes and engaging in pleasurable activities, individuals can actively improve their physiological resilience and overall quality of life.

Experts in the field of behavioral medicine often cite this work for its accessible synthesis of complex biological data and psychological theory. Readers frequently note that the text provides a balanced, evidence-based approach to wellness that avoids common self-help platitudes.