
<p>This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful <i>Methods in Molecular Biology </i>series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.</p> <p>Authoritative and cutting-edge, <i>Computational Biology of Non-Coding RNA: Methods and Protocols </i>aims to provide a state-of-the-art collection of computational methodsand approaches that will be of value to researchers interested in ncRNA field. </p><br>
Page Count:
451
Publication Date:
2019-01-12
ISBN-10:
1493989812
ISBN-13:
9781493989812
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